Mouse Ear Irradiation Model

We have developed equipment, techiques and protocols that allow us to irradiate a mouse ear using the charged-particle microbeam.

The ear of a mouse, measuring approximately 13 mm in both length and width and with an average thickness of 250 µm, can be used for bystander studies in vivo with our 5-MeV proton microbeam, which has a range of 350 µm. It is possible to irradiate a small area of the mouse ear and investigate bystander effects in non-targeted regions.

If you are looking to do animal irradiations at RARAF, contact the RARAF staff before planning as any irradiation/handling protocols will be required to submit a research plan for approval to the Columbia University Institutional Animal Care and Use Committee (IACUC)