Nikolaev A., Oks E.M., Savkin K., Yushkov G.Yu., Brenner
D.J., Johnson G., Randers-Pehrson G., Brown I.G. and MacGill
R.A. Surface resistivity tailoring of ceramic insulators
for an ion microprobe application. Surface & Coatings
Technology 201:8120-8122 (2007).
[PDF 219
KB]
Sedelnikova O.A., Nakamura A., Kovalchuk O., Koturbash I., Mitchell
S.A., Marino S.A., Brenner D.J. and Bonner W.M. DNA double-strand breaks
form in bystander cells after microbeam irradiation of three-dimensional
human tissue models. Cancer Res. 67:4295-4302
(2007). [abstract]
[PDF
621 KB]
Koh E.S., Tran T.H., Heydarian M., Sachs R.K., Tsang R.W., Brenner
D.J., Pintilie M., Xu T., Chung J., Paul N. and Hodgson D.C. A comparison
of mantle versus involved-field radiotherapy for Hodgkin's lymphoma:
reduction in normal tissue dose and second cancer risk. Radiat.
Oncol. 2:13 (2007). [abstract]
[PDF
1.17 MB]
Brenner D.J. Induced second cancers after prostate-cancer radiotherapy:
No cause for concern? Int. J. Radiat. Oncol. Biol. Phys. 65:637-639
(2006). [PDF
66 KB]
Brenner D.J. It is time to retire the computed tomography
dose index (CTDI) for CT quality assurance and dose optimization.
Med. Phys. 33:1189-1190 (2006).
[PDF
97 KB]
Brenner D.J. and Sachs R.K. Estimating radiation-induced cancer risks
at very low doses: rationale for using a linear no-threshold approach.
Radiat. Environ. Biophys. 44:253-256 (2006). [abstract]
[PDF
92 KB]
Garty G., Ross G.J., Bigelow A.W., Randers-Pehrson G. and Brenner D.J.
Testing the stand-alone microbeam at Columbia University. Radiat.
Prot. Dosimetry 122:292-296 (2006). [abstract]
[PDF165
KB]
Hall E.J., Worgul B.V., Smilenov L., Elliston C.D. and Brenner D.J.
The relative biological effectiveness of densely ionizing heavy-ion
radiation for inducing ocular cataracts in wild type versus mice heterzygous
for the ATM gene. Radiat. Environ. Biophys. 45:99-104
(2006).[abstract]
[PDF 409
KB]
Shuryak I., Sachs R.K., Hlatky L., Little M.P., Hahnfeldt P. and Brenner
D.J. Radiation-induced leukemia at doses relevant to radiation therapy:
Modeling mechanisms and estimating risks. JNCI 98:1974-1806
(2006). [abstract]
[PDF
790 KB]
Ross G.J., Bigelow A.W., Randers-Pehrson G., Peng C.C. and Brenner
D.J. Phase-based cell imaging techniques for microbeam irradiations.
Nucl. Instrum. Methods Phys. Res. B 241:387-391
(2005). [PDF
188 KB]
Garty G., Ross G.J., Bigelow A., Randers-Pehrson G. and Brenner D.J.
A microbeam irradiator without an accelerator. Nucl. Instrum. Methods
Phys. Res. B 241 392-396 (2005). [PDF
203 KB]
Bigelow A.W., Randers-Pehrson G., Kelly R.P. and Brenner
D.J. Laser ion source for Columbia University's microbeam.
Nucl. Instrum. Methods Phys. Res. B 241:
874-879 (2005). [PDF
261 KB]
Garty G., Randers-Pehrson G. and Brenner D.J. Development
of a secondary-electron ion-microscope for microbeam diagnostics.
Nucl. Instrum. Methods Phys. Res. B 231:60-64
(2005) [PDF 308 KB]
Bigelow A.W., Ross G.J., Randers-Pehrson G. and Brenner
D.J. The Columbia University Microbeam II endstation for
cell imaging and irradiation. Nucl. Instrum. Methods
Phys. Res. B 231:202-206 (2005)
[PDF 190 KB]
Ross G.J., Garty G., Randers-Pehrson G. and Brenner D.J.
A single-particle/single-cell microbeam based on an isotopic
alpha source. Nucl. Instrum. Methods Phys. Res. B
231:207-211 (2005) [PDF
300 KB]
Zhou H., Ivanov V.N., Gillespie J., Geard C.R., Amundson
S.A., Brenner D.J., Yu Z., Lieberman H.B. and Hei T.K.
Mechanism of radiation-induced bystander effect: role
of the cyclooxygenase-2 signaling pathway. PNAS
102:14641-14646 (2005) [abstract]
[PDF
493 KB]
Brenner D.J. Letter to the Editor: Is it time to retire the CTDI for
CT quality assurance and dose optimization? Med. Phys. 32:3225-3226
(2005). [PDF
44 KB]
Belyakov O.V., Mitchell S.A., Parikh D., Randers-Pehrson G., Marino
S.A., Amundson S.A., Geard C.R. and Brenner D.J. Biological effects in
unirradiated human tissue induced by radiation damage up to 1 mm away.
PNAS 102:14203-14208 (2005) [abstract]
[PDF
675 KB]
Sachs R.K. and Brenner D.J. Solid tumor risks after high doses of
ionizing radiation. PNAS 102:13040-13045 (2005). [abstract]
[PDF
436 KB]
Brenner D.J. and Georgsson M.A. Mass Screening With CT Colonography:
Should the radiation exposure be of concern? Gastroenterology
129:328-337 (2005). [abstract]
[PDF
489 KB]
Hall E.J., Brenner D.J., Worgul B. and Smilenov L. Genetic
susceptibility to radiation. Adv. Space Res. 35:249-253
(2005). [abstract]
[PDF
165 KB]
Hande M.P., Azizova T.V., Burak L.E., Khokhryakov V.F., Geard C.R.
and Brenner D.J. Complex chromosome aberrations persist in individuals
many years after occupational exposure to densely ionizing radiation: An
mFISH study. Genes Chromosomes Cancer 44:1-9 (2005). [abstract]
[PDF
234 KB]
Vives S., Loucas B., Vazquez M., Brenner D.J., Sachs R.K., Hlatky L.,
Cornforth M., Arsuaga J. SCHIP: statistics for chromosome interphase
positioning based on interchange data. Bioinformatics 21:3181-3182
(2005). [abstract]
[PDF
94 KB]
Worgul B.V., Smilenov L., Brenner D.J., Vazquez M., Hall E.J. Mice
heterozygous for the ATM gene are more sensitive to both X-ray and heavy
ion exposure than are wildtypes. Adv. Space Res. 35:254-259
(2005). [abstract]
[PDF
157 KB]
Brenner D.J. and Elliston C.D. In response to Radiation risk of body
CT: What to tell our patients and other questions. (R.E. Levatter)
Radiology 234:968-970 (2005). [abstract]
[PDF 200 KB]
Brenner D.J. Fractionation and late rectal toxicology. Int. J.
Radiat. Oncol. Biol. Phys. 60:1013-1015 (2004). [abstract]
[PDF
80 KB]
Ponnaiya B., Jenkins-Baker G., Brenner D.J., Hall E.J.,
Randers-Pehrson G. and Geard C.R. Biological responses in known
bystander cells relative to known microbeam-irradiated cells. Radiat.
Res. 162:426-432 (2004). [abstract]
[PDF
148 KB]
Mitchell C.R., Azizova T.V., Hande M.P., Burak L.E., Tsakok J.M.,
Khokhryakov V.F., Geard C.R. and Brenner D.J. Stable intrachromosomal
biomarkers of past exposure to densely ionizing radiation in several
chromosomes of exposed individuals. Radiat. Res. 162:257-263
(2004). [abstract]
[PDF
176 KB]
Arsuaga J., Greulich-Bose K.M., Vazquez M., Bruckner M., Hahnfeldt
P., Brenner D.J., Sachs R. and Hlatky L. Chromosome spatial clustering
inferred from radiogenic aberrations. Int. J. Radiat. Biol. 80:507-515
(2004). [abstract]
[PDF
340 KB]
Brenner D.J. and Elliston C.D. Estimated radiation risks potentially
associated with full-body CT screening. Radiology 232:735-738
(2004). [abstract]
[PDF
131 KB]
Mitchell S.A., Marino S.A., Brenner D.J. and Hall E.J. Bystander
effect and adaptive response in C3H 10T½ cells. Int. J. Radiat. Biol.
80:465-472 (2004). [PDF
248 KB]
Brenner D.J. and Hall E.J. Risk of cancer from diagnostic X-rays.
Lancet 363:2192 (2004). [abstract]
[PDF
55 KB]
Brenner D.J. Radiation risks potentially associated with low-dose CT
screening of adult smokers for lung cancer. Radiology 231:440-445
(2004). [abstract]
[PDF
158 KB]
Mitchell S.A., Randers-Pehrson G., Brenner D.J. and Hall E.J. The
Bystander Response in C3H 10T(1/2) Cells: The Influence of Cell-to-Cell
Contact. Radiat. Res. 161:397-401 (2004). [abstract]
[PDF
89 KB]
Brenner D.J., Doll R., Goodhead D.T., Hall E.J., et al. Cancer
risks attributable to low doses of ionizing radiation: Assessing what we
really know. Proc. Natl. Acad. Sci. USA 100:13761-13766
(2003). [abstract]
[PDF
328 KB]
Brenner D.J. Hypofractionation for prostate cancer radiotherapy––what
are the issues? Int. J. Radiat. Oncol. Biol. Phys. 57:912-914
(2003). [abstract]
[PDF
93 KB]
Zhou H., Randers-Pehrson G., Geard C.R., Brenner D.J., Hall E.J. and
Hei T.K. Interaction between radiation-induced adaptive response and
bystander mutagenesis in mammalian cells. Radiat. Res. 160:512-516
(2003). [abstract]
[PDF
243 KB]
Hall E.J. and Brenner D.J. The weight of evidence does not support
the suggestion that exposure to low doses of X rays increases longevity.
Radiology 229:18-19 (2003). [abstract]
[PDF
66 KB]
Fowler J.F., Ritter M.A., Chappell R.J. and Brenner D.J. What
hypofractionated protocols should be tested for prostate cancer? Int.
J. Radiat. Oncol. Biol. Phys. 56:1093-1104 (2003). [abstract]
[PDF
269 KB]
Brenner D.J. and Sachs R.K. Domestic radon risks may be dominated by
bystander effects- But the risks are unlikely to be greater than we
thought. Heath Phys 85:103-108 (2003). [abstract]
[PDF
400 KB]
Hande M.P., Azizova T.V., Geard C.R., Burak L.E., Mitchell C.R.,
Khokhryakov V.F., Vasilenko E.K. and Brenner D.J. Past exposure to
densely ionizing radiation leaves a unique permanent signature in the
genome. Am. J. Hum. Genet. 72:1162-1170 (2003). [abstract]
[PDF 792
KB]
Brenner D.J. and Hall E.J. Mortality patterns in British and US
radiologists: what can we really conclude? BJR 76:1-2
(2003). [abstract]
[PDF 42 KB]
Cornforth M.N., Greulich-Bode K.M., Loucas B.D., Arsuaga J., Vázquez
M., Sachs R.K., Brückner M., Molls M., Hahnfeldt P., Hlatky L. and
Brenner D.J. Chromosomes are predominantly located randomly with respect
to each other in interphase human cells. J. Cell Biol. 159:237-244
(2002). [abstract]
[PDF 128 KB]
Brenner D.J., Sawant S.G., Hande M.P., Miller R.C., Elliston C.D., Fu
Z., Randers-Pehrson G. and Marino SA. Routine screening mammography: how
important is the radiation-risk side of the benefit-risk equation?
Int. J. Radiat. Biol. 78:1065-1067 (2002) [abstract]
[PDF 125
KB]
Brenner D.J. and Hall E.J. Microbeams: a potent mix of physics and
biology. Summary of the 5th International Workshop on Microbeam Probes
of Cellular Radiation Response. Radiat. Prot. Dosimetry 99:283-286
(2002) [abstract]
Worgul B.V., Smilenov L., Brenner D.J., Junk A., Zhou W. and Hall
E.J. Atm heterozygous mice are more sensitive to radiation-induced
cataracts than are their wild-type counterparts. Proc. Natl. Acad.
Sci. USA 99:9836-9839 (2002). [abstract]
[PDF 158
KB]
Brenner D.J. and Sachs R.K. Do low dose-rate bystander effects
influence domestic radon risks? Int. J. Radiat. Biol. 78:593-604
(2002). [abstract]
[PDF 318
KB]
Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D.
and Armour E.P. Direct evidence that prostate tumors show high
sensitivity to fractionation (low a/b
ratio), similar to late-responding normal tissue. Int. J.
Radiat. Oncol. Biol. Phys. 52:6-13 (2002). [abstract]
[PDF 157 KB]
Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D.
and Armour E.P. In response to Dr. Lee. Int. J. Radiat. Oncol. Biol.
Phys. 53:1393 (2002) [abstract]
[PDF 21 KB]
Brenner D.J. Estimating cancer risks from pediatric CT: Going from
the qualitative to the quantitative.. Pediatr. Radiol. 32:228-231
(2002). [abstract]
[PDF 46 KB]
Brenner D.J. and Elliston C.D. The potential impact of bystander
effects on radiation risks in a Mars mission. Radiat. Res. 156:612-617
(2001). [abstract]
[PDF 122
KB]
Brenner D.J., Elliston C.D., Hall E.J. and Berdon W.E. Estimated
risks of radiation-induced fatal cancer from pediatric CT. AJR
176:289-296 (2001). [abstract]
[PDF 99 KB]
Brenner D.J. and Hall E.J. Dose rate does matter in
endovascular brachytherapy. Cardiovasc. Radiat. Med. 2:254-255
(2001). [abstract]
[PDF 58 KB]
Brenner D.J., Little J.B. and Sachs R.K. The bystander effect in
radiation oncogenesis II. A quantitative model. Radiat. Res.
155:402-408 (2001). [abstract]
[PDF 141
KB]
Brenner D.J. and Miller R.C. Long-term efficacy of intracoronary
irradiation in inhibiting in-stent restenosis. Circulation 103:1330-1332
(2001). [abstract]
[PDF 44 KB]
Brenner D.J., Okladnikova N., Hande P., Burak L., Geard C.R. and
Azizova T. Biomarkers specific to densely-ionising (high LET)
radiations. Radiat. Prot. Dosimetry 97:69-73 (2001). [abstract]
Brenner D.J. and Raabe O.G. Topics Under Debate: Is the
Linear-No-Threshold Hypothesis Appropriate for Use in Radiation
Protection? Radiat. Prot. Dosim. 97: 279-285 (2001). [abstract]
[PDF 230 KB]
Ponomarev A.L., Cucinotta F.A., Sachs R.K., Brenner D.J. and Peterson
L.E. Extrapolation of the DNA fragment-size distribution after high-dose
irradiation to predict effects at low doses. Radiat. Res.
156:594-597 (2001). [abstract]
[PDF 63
KB]
Ponomarev A.L., Cucinotta F.A., Sachs R.K. and Brenner D.J. Monte
Carlo predictions of DNA fragment-sized distributions for large sizes
after HZE particle irradiation. Phys. Med. 17:153-6 Suppl.
(2001). [abstract]
[PDF 322 KB]
Randers-Pehrson G., Geard C.R., Johnson G., Elliston C.D. and Brenner
D.J. The Columbia University single-ion microbeam. Radiat. Res.
156:210-214 (2001). [abstract]
[PDF 278
KB]
Sawant S.G., Randers-Pehrson G., Geard C.R., Brenner D.J. and Hall
E.J. The bystander effect in radiation oncogenesis I. Transformation in
C3H 10T1/2 cells in vitro can be initiated in the unirradiated
neighbors of irradiated cells. Radiat. Res. 155:397-401
(2001). [abstract]
[PDF 142
KB]
Smilenov L.B., Brenner D.J. and Hall E.J. Modest increased
sensitivity to radiation oncogenesis in ATM heterozygous versus
wild-type mammalian cells. Cancer Res. 61:5710-5713
(2001). [abstract]
[PDF 61
KB]
Brenner D.J. Towards optimal external-beam fractionation
for prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 48:315-316
(2000). [abstract]
[PDF 90 KB]
Brenner D.J., Curtis R.E., Hall E.J. and Ron E. Second
Malignancies in Prostate Cancer Patients After Radiotherapy Compared to
Surgery. Cancer 88:398-406 (2000). [abstract]
[PDF 116
KB]
Brenner D.J. and Sachs R.K. Protraction effects in
radiation studies: basic biophysics. Radiat. Res. 156:736-737
(2000). [abstract]
[PDF 31
KB]
Brenner D.J., Schiff P.B. and Zablotska L.B. Adjuvant radiotherapy
for DCIS. Lancet 355:2071 (2000). [abstract]
[PDF 514
KB]
Dymnikov A.D., Brenner D.J., Johnson G. and Randers-Pehrson G.
Theoretical study of short electrostatic lens for the Columbia ion
microprobe. Rev. Sci. Instr. 71:1646-1650
(2000). [abstract]
[PDF 126 KB]
Miller R.C., Marino, S.A., Napoli J., Shah H., Hall, E.J., Geard C.R.
and Brenner D.J. Oncogenic transformation in C3H10T½ cells by low-energy
neutrons. Int. J. Radiat. Biol. 76:327-334 (2000). [abstract]
[PDF 172
KB]
Ponomarev A.L., Brenner D.J., Hlatky L.R., and Sachs R.K. A polymer,
random walk model for the size-distribution of large DNA fragments after
high linear energy transfer radiation. Radiat. Environ. Biophys.
39:111-120 (2000). [abstract]
[PDF 92 KB]
Brenner D.J. Does fractionation decrease the risk of breast cancer
induced by low-LET radiation? Radiat. Res. 151:225-229
(1999). [abstract]
Brenner D.J. The relative effectiveness of exposure to
131I at low doses. Health Phys.
76:180-185 (1999). [abstract]
Brenner D.J. and Hall E.J. Fractionation and protraction for
radiotherapy of prostate carcinoma. Int. J. Radiat. Oncol. Biol.
Phys. 43:1095-1101 (1999). [abstract]
[PDF 97 KB]
Brenner D.J., Leu C-S, Beatty J.F., and Shefer R.E. Clinical relative
biological effectiveness of low-energy x-ray emitted by miniature x-ray
devices. Phys. Med. Biol. 44:323-333 (1999). [abstract]
[PDF 156 KB]
Brenner D.J. and Sachs R.K. A more robust biologically based ranking
criterion for treatment plans. Int. J. Radiat. Oncol. Biol. Phys.
43:697-698 (1999). [abstract]
[PDF 44 KB]
Hall E.J., Miller R.C. and Brenner D.J. Radiobiological principles in
intravascular irradiation. Cardiovasc. Radiat. Med. 1:42-47
(1999). [abstract]
[PDF 353 KB]
Johnson K.L., Brenner D.J., Geard C.R., Nath J., and Tucker J.D.
Chromosome aberrations of clonal origin in irradiated and unexposed
individuals: Assessment and implications. Radiat. Res.
152:1-5 (1999). [abstract]
Johnson K.L., Brenner D.J., Nath J., Tucker J.D., and Geard C.R.
Radiation-induced breakpoint misrejoining in human chromosomes: Random
or non-random? Int. J. Radiat. Biol. 75:131-141
(1999). [abstract]
[PDF 211
KB]
Miller R.C., Marino S.A., Martin S.G., Komatsu K., Geard C.R.,
Brenner D.J. and Hall E.J. Neutron-energy-dependent cell survival and
oncogenic transformation. J. Radiat. Res. 40:53-59 Suppl
(1999). [abstract]
[PDF 58 KB]
Miller R.C., Randers-Pehrson G., Geard C.R., Hall E.J., and Brenner
D.J. The oncogenic transforming potential of the passage of single alpha
particles through mammalian cell nuclei. Proc. Nat. Acad. Sci. USA
96:18-22 (1999). [abstract]
[PDF 158
KB]
Smith L.G., Miller R.C., Richards M., Brenner D.J. and Hall E.J.
Investigation of hypersensitivity to fractionated low-dose radiation
exposure. Int. J. Radiat. Oncol. Biol. Phys. 45:187-191
(1999). [abstract]
[PDF 97 KB]
Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Huang Y., and Sachs R.K.
The linear-quadratic model and most other common radiobiological models
result in similar predictions of time-dose relationships. Radiat.
Res. 150:83-91 (1998). [abstract]
Brenner D.J., Lubin, J.H. and Ron E. Moving from under the lamppost:
can epidemiologists and radiobiologists work together? Nucl Med
37:25-31 (1998). [abstract]
[PDF 325 KB]
Hall E.J., Schiff P.B., Hanks G.E., Brenner D.J., Russo J., Chen J.
Sawant S.G., and Pandita T.K. A preliminary report: Frequency of A-T
heterozygotes among prostate cancer patients with severe late responses
to radiation therapy. Cancer J. Sci. Am. 4:385-389
(1998). [abstract]
Randers-Pehrson G. and Brenner D.J. A practical target system for
accelerator-based BNCT which may effectively double the dose rate.
Med. Phys. 25:894-6 (1998). [abstract]
[PDF 70
KB]
Sachs R.K., Brenner D.J., Hahnfeldt P.J. and Hlatky L.R. A formalism
for analysing large-scale clustering of radiation-induced breaks along
chromosomes. Int. J. Radiat. Biol. 74:185-206
(1998). [abstract]
[PDF 499
KB]
Brenner D. J. Radiation biology in brachytherapy. J. Surg. Oncol.
65:66-70 (1997). [abstract]
[PDF 220 KB]
Brenner D.J., Schiff P.B., Huang Y., and Hall E.J. Pulsed dose-rate
(PDR) brachytherapy: Design of convenient (daytime only) schedules.
Int. J. Radiat. Oncol. Biol. Phys. 39: 809-815
(1997). [abstract]
[PDF 599 KB]
Sachs R.K., Hahnfeld P., and Brenner D.J. Review: The link between
low-LET dose-response relations and the underlying kinetics of damage
production/repair/misrepair. Int. J. Radiat. Biol. 72:351-374
(1997). [abstract]
[PDF 606KB]
Sachs R.K., Chen A.M., and Brenner D.J. Review: Proximity effects in
the production of chromosome aberrations by ionizing radiation. Int.
J. Radiat. Biol. 71:1-19 (1997). [abstract]
[PDF 420
KB]
Brenner D.J. Direct biological evidence for a significant neutron
dose to survivors of the hiroshima A bomb. Radiat. Res.
145:501-507 (1996). [abstract]
Brenner D.J., Hall E.J., Randers-Pehrson G., Huang Y., Johnson G.W.,
Miller R.W., Wu B., Vazquez M.E., Medvedovsky C. and Worgul B.V.
Quantitative comparisons of continuous and pulsed low dose-rate regimens
in a model late-effect system. Int. J. Radiat. Oncol. Biol. Phys.
34:905-910 (1996). [abstract]
[PDF 494 KB]
Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Hall E.J., and Sachs R.K.
A convenient extension of the linear-quadratic model to include
redistribution and reoxygenation. Int. J. Radiat. Oncol. Biol. Phys.
32:379-390 (1995). [abstract]
[PDF 1007
KB]
Brenner D.J., Miller R.C., Huang Y. and Hall E.J. The biological
effectiveness of radon-progeny aplha particles. III. Quality factors.
Radiat. Res. 142:61-69 (1995). [abstract]
Brenner D.J. and Sachs R.K. Chromosomal 'fingerprints' of prior
exposure to densely-ionizing radiation. Radiat. Res.
140:134-142 (1994). [abstract]
Brenner D.J., Hall E.J., Huang Y.P., and Sachs R.K. Optimizing the
time course of brachytherapy and other accelerated radiotherapeutic
protocols. Int. J. Radiat. Oncol. Biol. Phys. 29:893-901
(1994). [abstract]
Brenner D.J. The significance of dose rate in assessing the hazards
of domestic radon exposure. Health Physics 67:76-79
(1994). [abstract]
Hahnfeldt P., Hearst J.E., Brenner D.J., Sachs R.K., and Hlatky L.R.
Polymer models for interphase chromosomes. Proc. Nat. Acad. Sci. USA
90:7854-7858 (1993). [abstract]
[PDF 1035
KB]