David Jonathan Brenner
RARAF Director


 
  Research Interests
  • Biophysical modeling

  • Radiation biology

  • Low dose risk estimation

  • Radiotherapy

  • Radon
   

Contact Information

David J. Brenner
Center for Radiological Research
VC 11-234/235
630 W. 168th St.
New York, NY 10032

Tel: (212) 305-9930
Fax: (212) 305-3229
email: djb3@columbia.edu

 
 

Academic Training  
 

Undergraduate:

  • B.A., Physics Philosophy, Oxford University, Oxford, U.K., 1974

Graduate:

  • M.Sc., Radiation Physics, St. Bartholomew's Hospital, University of London, London, U.K., 1976

  • M.A., Physics Philosophy, Oxford University, Oxford, U.K., 1979

  • Ph.D. Physics, University of Surrey, Guildford, U.K., 1980

  • D.Sc. Honorary Degree, Oxford University, 1996

 
 


Current Academic and Professional Appointments  


Current Research  

David Brenner focuses on developing models for the effects of ionizing radiation on living systems, both at the chromosomal and the animal (or human) levels. He divides his research time roughly equally between the effects of high doses of ionizing radiation (relating to radiation therapy) and the effects of low doses of radiation (relating to environmental and occupational exposures).

Environmentally, he has focused on the biological effects of radon, both at the chromosomal and the human levels. In the field of radiotherapy, he has focused on optimizing fractionation schemes for different tumor types (how the total treatment is divided up into different individual sessions), to maximize tumor killing and minimize serious side effects in normal tissues.

Brenner is the author of two books on radiation for the lay person: Making the Radiation Therapy Decision and Radon, Risk and Remedy. Additionally, he has published more than 160 papers in the peer-reviewed scientific literature. He was the recipient of the 1991 Radiation Research Society Annual Research Award, and the 1992 National Council on Radiation Protection and Measurements Award for Radiation Protection in Medicine.

 
 

Curriculum Vitae  

Click here to download a full CV (requires Adobe Acrobat Reader, available for free download here: )

 
 

Select Publications Online  

Some papers are available online in PDF format (requires Adobe Acrobat Reader, available for free download from Adobe).

If you do not find what you are looking for below, try searching for David Brenner on PubMed.

Nikolaev A., Oks E.M., Savkin K., Yushkov G.Yu., Brenner D.J., Johnson G., Randers-Pehrson G., Brown I.G. and MacGill R.A. Surface resistivity tailoring of ceramic insulators for an ion microprobe application. Surface & Coatings Technology 201:8120-8122 (2007). [PDF 219 KB]

Sedelnikova O.A., Nakamura A., Kovalchuk O., Koturbash I., Mitchell S.A., Marino S.A., Brenner D.J. and Bonner W.M. DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Res. 67:4295-4302 (2007). [abstract] [PDF 621 KB]

Koh E.S., Tran T.H., Heydarian M., Sachs R.K., Tsang R.W., Brenner D.J., Pintilie M., Xu T., Chung J., Paul N. and Hodgson D.C. A comparison of mantle versus involved-field radiotherapy for Hodgkin's lymphoma: reduction in normal tissue dose and second cancer risk. Radiat. Oncol. 2:13 (2007). [abstract] [PDF 1.17 MB]

Brenner D.J. Induced second cancers after prostate-cancer radiotherapy: No cause for concern? Int. J. Radiat. Oncol. Biol. Phys. 65:637-639 (2006). [PDF 66 KB]

Brenner D.J. It is time to retire the computed tomography dose index (CTDI) for CT quality assurance and dose optimization. Med. Phys. 33:1189-1190 (2006). [PDF 97 KB]

Brenner D.J. and Sachs R.K. Estimating radiation-induced cancer risks at very low doses: rationale for using a linear no-threshold approach. Radiat. Environ. Biophys. 44:253-256 (2006). [abstract] [PDF 92 KB]

Garty G., Ross G.J., Bigelow A.W., Randers-Pehrson G. and Brenner D.J. Testing the stand-alone microbeam at Columbia University. Radiat. Prot. Dosimetry 122:292-296 (2006). [abstract] [PDF165 KB]

Hall E.J., Worgul B.V., Smilenov L., Elliston C.D. and Brenner D.J. The relative biological effectiveness of densely ionizing heavy-ion radiation for inducing ocular cataracts in wild type versus mice heterzygous for the ATM gene. Radiat. Environ. Biophys. 45:99-104 (2006).[abstract] [PDF 409 KB]

Shuryak I., Sachs R.K., Hlatky L., Little M.P., Hahnfeldt P. and Brenner D.J. Radiation-induced leukemia at doses relevant to radiation therapy: Modeling mechanisms and estimating risks. JNCI 98:1974-1806 (2006). [abstract] [PDF 790 KB]

Ross G.J., Bigelow A.W., Randers-Pehrson G., Peng C.C. and Brenner D.J. Phase-based cell imaging techniques for microbeam irradiations. Nucl. Instrum. Methods Phys. Res. B 241:387-391 (2005). [PDF 188 KB]

Garty G., Ross G.J., Bigelow A., Randers-Pehrson G. and Brenner D.J. A microbeam irradiator without an accelerator. Nucl. Instrum. Methods Phys. Res. B 241  392-396 (2005). [PDF 203 KB]

Bigelow A.W., Randers-Pehrson G., Kelly R.P. and Brenner D.J. Laser ion source for Columbia University's microbeam. Nucl. Instrum. Methods Phys. Res. B 241: 874-879 (2005). [PDF 261 KB]

Garty G., Randers-Pehrson G. and Brenner D.J. Development of a secondary-electron ion-microscope for microbeam diagnostics. Nucl. Instrum. Methods Phys. Res. B 231:60-64 (2005) [PDF 308 KB]

Bigelow A.W., Ross G.J., Randers-Pehrson G. and Brenner D.J. The Columbia University Microbeam II endstation for cell imaging and irradiation. Nucl. Instrum. Methods Phys. Res. B 231:202-206 (2005) [PDF 190 KB]

Ross G.J., Garty G., Randers-Pehrson G. and Brenner D.J. A single-particle/single-cell microbeam based on an isotopic alpha source. Nucl. Instrum. Methods Phys. Res. B 231:207-211 (2005) [PDF 300 KB]

Zhou H., Ivanov V.N., Gillespie J., Geard C.R., Amundson S.A., Brenner D.J., Yu Z., Lieberman H.B. and Hei T.K. Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. PNAS 102:14641-14646 (2005) [abstract] [PDF 493 KB]

Brenner D.J. Letter to the Editor: Is it time to retire the CTDI for CT quality assurance and dose optimization? Med. Phys. 32:3225-3226 (2005). [PDF 44 KB]

Belyakov O.V., Mitchell S.A., Parikh D., Randers-Pehrson G., Marino S.A., Amundson S.A., Geard C.R. and Brenner D.J. Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away. PNAS 102:14203-14208 (2005) [abstract] [PDF 675 KB]

Sachs R.K. and Brenner D.J. Solid tumor risks after high doses of ionizing radiation. PNAS 102:13040-13045 (2005). [abstract] [PDF 436 KB]

Brenner D.J. and Georgsson M.A. Mass Screening With CT Colonography: Should the radiation exposure be of concern? Gastroenterology 129:328-337 (2005). [abstract] [PDF 489 KB]

Hall E.J., Brenner D.J., Worgul B. and Smilenov L. Genetic susceptibility to radiation. Adv. Space Res. 35:249-253 (2005). [abstract] [PDF 165 KB]

Hande M.P., Azizova T.V., Burak L.E., Khokhryakov V.F., Geard C.R. and Brenner D.J. Complex chromosome aberrations persist in individuals many years after occupational exposure to densely ionizing radiation: An mFISH study. Genes Chromosomes Cancer 44:1-9 (2005). [abstract] [PDF 234 KB]

Vives S., Loucas B., Vazquez M., Brenner D.J., Sachs R.K., Hlatky L., Cornforth M., Arsuaga J. SCHIP: statistics for chromosome interphase positioning based on interchange data. Bioinformatics 21:3181-3182 (2005). [abstract] [PDF 94 KB]

Worgul B.V., Smilenov L., Brenner D.J., Vazquez M., Hall E.J. Mice heterozygous for the ATM gene are more sensitive to both X-ray and heavy ion exposure than are wildtypes. Adv. Space Res. 35:254-259 (2005). [abstract] [PDF 157 KB]

Brenner D.J. and Elliston C.D. In response to Radiation risk of body CT: What to tell our patients and other questions. (R.E. Levatter) Radiology 234:968-970 (2005). [abstract] [PDF 200 KB]

Brenner D.J. Fractionation and late rectal toxicology. Int. J. Radiat. Oncol. Biol. Phys. 60:1013-1015 (2004). [abstract] [PDF 80 KB]

Ponnaiya B., Jenkins-Baker G., Brenner D.J., Hall E.J., Randers-Pehrson G. and Geard C.R. Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiat. Res. 162:426-432 (2004). [abstract] [PDF 148 KB]

Mitchell C.R., Azizova T.V., Hande M.P., Burak L.E., Tsakok J.M., Khokhryakov V.F., Geard C.R. and Brenner D.J. Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals. Radiat. Res. 162:257-263 (2004). [abstract] [PDF 176 KB]

Arsuaga J., Greulich-Bose K.M., Vazquez M., Bruckner M., Hahnfeldt P., Brenner D.J., Sachs R. and Hlatky L. Chromosome spatial clustering inferred from radiogenic aberrations. Int. J. Radiat. Biol. 80:507-515 (2004). [abstract] [PDF 340 KB]

Brenner D.J. and Elliston C.D. Estimated radiation risks potentially associated with full-body CT screening. Radiology 232:735-738 (2004).  [abstract] [PDF 131 KB]

Mitchell S.A., Marino S.A., Brenner D.J. and Hall E.J. Bystander effect and adaptive response in C3H 10T½ cells. Int. J. Radiat. Biol. 80:465-472 (2004). [PDF 248 KB]

Brenner D.J. and Hall E.J. Risk of cancer from diagnostic X-rays. Lancet 363:2192 (2004). [abstract] [PDF 55 KB]

Brenner D.J. Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer. Radiology 231:440-445 (2004). [abstract] [PDF 158 KB]

Mitchell S.A., Randers-Pehrson G., Brenner D.J. and Hall E.J. The Bystander Response in C3H 10T(1/2) Cells: The Influence of Cell-to-Cell Contact. Radiat. Res. 161:397-401 (2004). [abstract] [PDF 89 KB]

Brenner D.J., Doll R., Goodhead D.T., Hall E.J., et al. Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know. Proc. Natl. Acad. Sci. USA 100:13761-13766 (2003). [abstract] [PDF 328 KB]

Brenner D.J. Hypofractionation for prostate cancer radiotherapy––what are the issues? Int. J. Radiat. Oncol. Biol. Phys. 57:912-914 (2003). [abstract] [PDF 93 KB]

Zhou H., Randers-Pehrson G., Geard C.R., Brenner D.J., Hall E.J. and Hei T.K. Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells. Radiat. Res. 160:512-516 (2003). [abstract] [PDF 243 KB]

Hall E.J. and Brenner D.J. The weight of evidence does not support the suggestion that exposure to low doses of X rays increases longevity. Radiology 229:18-19 (2003). [abstract] [PDF 66 KB]

Fowler J.F., Ritter M.A., Chappell R.J. and Brenner D.J. What hypofractionated protocols should be tested for prostate cancer? Int. J. Radiat. Oncol. Biol. Phys. 56:1093-1104 (2003). [abstract] [PDF 269 KB]

Brenner D.J. and Sachs R.K. Domestic radon risks may be dominated by bystander effects- But the risks are unlikely to be greater than we thought. Heath Phys 85:103-108 (2003). [abstract] [PDF 400 KB]

Hande M.P., Azizova T.V., Geard C.R., Burak L.E., Mitchell C.R., Khokhryakov V.F., Vasilenko E.K. and Brenner D.J. Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome. Am. J. Hum. Genet. 72:1162-1170 (2003). [abstract] [PDF 792 KB]

Brenner D.J. and Hall E.J. Mortality patterns in British and US radiologists: what can we really conclude? BJR 76:1-2 (2003). [abstract] [PDF 42 KB]

Cornforth M.N., Greulich-Bode K.M., Loucas B.D., Arsuaga J., Vázquez M., Sachs R.K., Brückner M., Molls M., Hahnfeldt P., Hlatky L. and Brenner D.J. Chromosomes are predominantly located randomly with respect to each other in interphase human cells. J. Cell Biol. 159:237-244 (2002). [abstract] [PDF 128 KB]

Brenner D.J., Sawant S.G., Hande M.P., Miller R.C., Elliston C.D., Fu Z., Randers-Pehrson G. and Marino SA. Routine screening mammography: how important is the radiation-risk side of the benefit-risk equation? Int. J. Radiat. Biol. 78:1065-1067 (2002) [abstract] [PDF 125 KB]

Brenner D.J. and Hall E.J. Microbeams: a potent mix of physics and biology. Summary of the 5th International Workshop on Microbeam Probes of Cellular Radiation Response. Radiat. Prot. Dosimetry 99:283-286 (2002) [abstract]

Worgul B.V., Smilenov L., Brenner D.J., Junk A., Zhou W. and Hall E.J. Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts. Proc. Natl. Acad. Sci. USA 99:9836-9839 (2002). [abstract] [PDF 158 KB]

Brenner D.J. and Sachs R.K. Do low dose-rate bystander effects influence domestic radon risks? Int. J. Radiat. Biol. 78:593-604 (2002). [abstract] [PDF 318 KB]

Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D. and Armour E.P. Direct evidence that prostate tumors show high sensitivity to fractionation (low a/b ratio), similar to late-responding normal tissue. Int. J. Radiat. Oncol. Biol. Phys. 52:6-13 (2002). [abstract] [PDF 157 KB]

Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D. and Armour E.P. In response to Dr. Lee. Int. J. Radiat. Oncol. Biol. Phys. 53:1393 (2002) [abstract] [PDF 21 KB]

Brenner D.J. Estimating cancer risks from pediatric CT: Going from the qualitative to the quantitative.. Pediatr. Radiol. 32:228-231 (2002). [abstract] [PDF 46 KB]

Brenner D.J. and Elliston C.D. The potential impact of bystander effects on radiation risks in a Mars mission. Radiat. Res. 156:612-617 (2001). [abstract] [PDF 122 KB]

Brenner D.J., Elliston C.D., Hall E.J. and Berdon W.E. Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289-296 (2001). [abstract] [PDF 99 KB]

Brenner D.J. and Hall E.J. Dose rate does matter in endovascular brachytherapy. Cardiovasc. Radiat. Med. 2:254-255 (2001). [abstract] [PDF 58 KB]

Brenner D.J., Little J.B. and Sachs R.K. The bystander effect in radiation oncogenesis II. A quantitative model. Radiat. Res. 155:402-408 (2001). [abstract] [PDF 141 KB]

Brenner D.J. and Miller R.C. Long-term efficacy of intracoronary irradiation in inhibiting in-stent restenosis. Circulation 103:1330-1332 (2001). [abstract] [PDF 44 KB]

Brenner D.J., Okladnikova N., Hande P., Burak L., Geard C.R. and Azizova T. Biomarkers specific to densely-ionising (high LET) radiations. Radiat. Prot. Dosimetry 97:69-73 (2001). [abstract]

Brenner D.J. and Raabe O.G. Topics Under Debate: Is the Linear-No-Threshold Hypothesis Appropriate for Use in Radiation Protection? Radiat. Prot. Dosim. 97: 279-285 (2001). [abstract] [PDF 230 KB]

Ponomarev A.L., Cucinotta F.A., Sachs R.K., Brenner D.J. and Peterson L.E. Extrapolation of the DNA fragment-size distribution after high-dose irradiation to predict effects at low doses. Radiat. Res. 156:594-597 (2001). [abstract] [PDF 63 KB]

Ponomarev A.L., Cucinotta F.A., Sachs R.K. and Brenner D.J. Monte Carlo predictions of DNA fragment-sized distributions for large sizes after HZE particle irradiation. Phys. Med. 17:153-6 Suppl. (2001). [abstract] [PDF 322 KB]

Randers-Pehrson G., Geard C.R., Johnson G., Elliston C.D. and Brenner D.J. The Columbia University single-ion microbeam. Radiat. Res. 156:210-214 (2001). [abstract] [PDF 278 KB]

Sawant S.G., Randers-Pehrson G., Geard C.R., Brenner D.J. and Hall E.J. The bystander effect in radiation oncogenesis I. Transformation in C3H 10T1/2 cells in vitro can be initiated in the unirradiated neighbors of irradiated cells. Radiat. Res. 155:397-401 (2001). [abstract] [PDF 142 KB]

Smilenov L.B., Brenner D.J. and Hall E.J. Modest increased sensitivity to radiation oncogenesis in ATM heterozygous versus wild-type mammalian cells. Cancer Res. 61:5710-5713 (2001). [abstract] [PDF 61 KB]

Brenner D.J. Towards optimal external-beam fractionation for prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 48:315-316 (2000). [abstract] [PDF 90 KB]

Brenner D.J., Curtis R.E., Hall E.J. and Ron E. Second Malignancies in Prostate Cancer Patients After Radiotherapy Compared to Surgery. Cancer 88:398-406 (2000). [abstract] [PDF 116 KB]

Brenner D.J. and Sachs R.K. Protraction effects in radiation studies: basic biophysics. Radiat. Res. 156:736-737 (2000). [abstract] [PDF 31 KB]

Brenner D.J., Schiff P.B. and Zablotska L.B. Adjuvant radiotherapy for DCIS. Lancet 355:2071 (2000). [abstract] [PDF 514 KB]

Dymnikov A.D., Brenner D.J., Johnson G. and Randers-Pehrson G. Theoretical study of short electrostatic lens for the Columbia ion microprobe. Rev. Sci. Instr. 71:1646-1650 (2000). [abstract] [PDF 126 KB]

Miller R.C., Marino, S.A., Napoli J., Shah H., Hall, E.J., Geard C.R. and Brenner D.J. Oncogenic transformation in C3H10T½ cells by low-energy neutrons. Int. J. Radiat. Biol. 76:327-334 (2000). [abstract] [PDF 172 KB]

Ponomarev A.L., Brenner D.J., Hlatky L.R., and Sachs R.K. A polymer, random walk model for the size-distribution of large DNA fragments after high linear energy transfer radiation. Radiat. Environ. Biophys. 39:111-120 (2000). [abstract] [PDF 92 KB]

Brenner D.J. Does fractionation decrease the risk of breast cancer induced by low-LET radiation? Radiat. Res. 151:225-229 (1999). [abstract]

Brenner D.J. The relative effectiveness of exposure to 131I at low doses. Health Phys. 76:180-185 (1999). [abstract]

Brenner D.J. and Hall E.J. Fractionation and protraction for radiotherapy of prostate carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 43:1095-1101 (1999). [abstract] [PDF 97 KB]

Brenner D.J., Leu C-S, Beatty J.F., and Shefer R.E. Clinical relative biological effectiveness of low-energy x-ray emitted by miniature x-ray devices. Phys. Med. Biol. 44:323-333 (1999). [abstract] [PDF 156 KB]

Brenner D.J. and Sachs R.K. A more robust biologically based ranking criterion for treatment plans. Int. J. Radiat. Oncol. Biol. Phys. 43:697-698 (1999). [abstract] [PDF 44 KB]

Hall E.J., Miller R.C. and Brenner D.J. Radiobiological principles in intravascular irradiation. Cardiovasc. Radiat. Med. 1:42-47 (1999). [abstract] [PDF 353 KB]

Johnson K.L., Brenner D.J., Geard C.R., Nath J., and Tucker J.D. Chromosome aberrations of clonal origin in irradiated and unexposed individuals: Assessment and implications. Radiat. Res. 152:1-5 (1999). [abstract]

Johnson K.L., Brenner D.J., Nath J., Tucker J.D., and Geard C.R. Radiation-induced breakpoint misrejoining in human chromosomes: Random or non-random? Int. J. Radiat. Biol. 75:131-141 (1999). [abstract] [PDF 211 KB]

Miller R.C., Marino S.A., Martin S.G., Komatsu K., Geard C.R., Brenner D.J. and Hall E.J. Neutron-energy-dependent cell survival and oncogenic transformation. J. Radiat. Res. 40:53-59 Suppl (1999). [abstract] [PDF 58 KB]

Miller R.C., Randers-Pehrson G., Geard C.R., Hall E.J., and Brenner D.J. The oncogenic transforming potential of the passage of single alpha particles through mammalian cell nuclei. Proc. Nat. Acad. Sci. USA 96:18-22 (1999). [abstract] [PDF 158 KB]

Smith L.G., Miller R.C., Richards M., Brenner D.J. and Hall E.J. Investigation of hypersensitivity to fractionated low-dose radiation exposure. Int. J. Radiat. Oncol. Biol. Phys. 45:187-191 (1999). [abstract] [PDF 97 KB]

Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Huang Y., and Sachs R.K. The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships. Radiat. Res. 150:83-91 (1998). [abstract]

Brenner D.J., Lubin, J.H. and Ron E. Moving from under the lamppost: can epidemiologists and radiobiologists work together? Nucl Med 37:25-31 (1998). [abstract] [PDF 325 KB]

Hall E.J., Schiff P.B., Hanks G.E., Brenner D.J., Russo J., Chen J. Sawant S.G., and Pandita T.K. A preliminary report: Frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy. Cancer J. Sci. Am. 4:385-389 (1998). [abstract]

Randers-Pehrson G. and Brenner D.J. A practical target system for accelerator-based BNCT which may effectively double the dose rate. Med. Phys. 25:894-6 (1998). [abstract] [PDF 70 KB]

Sachs R.K., Brenner D.J., Hahnfeldt P.J. and Hlatky L.R. A formalism for analysing large-scale clustering of radiation-induced breaks along chromosomes. Int. J. Radiat. Biol. 74:185-206 (1998). [abstract] [PDF 499 KB]

Brenner D. J. Radiation biology in brachytherapy. J. Surg. Oncol. 65:66-70 (1997). [abstract] [PDF 220 KB]

Brenner D.J., Schiff P.B., Huang Y., and Hall E.J. Pulsed dose-rate (PDR) brachytherapy: Design of convenient (daytime only) schedules. Int. J. Radiat. Oncol. Biol. Phys. 39: 809-815 (1997). [abstract] [PDF 599 KB]

Sachs R.K., Hahnfeld P., and Brenner D.J. Review: The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair. Int. J. Radiat. Biol. 72:351-374 (1997). [abstract] [PDF 606KB]

Sachs R.K., Chen A.M., and Brenner D.J. Review: Proximity effects in the production of chromosome aberrations by ionizing radiation. Int. J. Radiat. Biol. 71:1-19 (1997). [abstract] [PDF 420 KB]

Brenner D.J. Direct biological evidence for a significant neutron dose to survivors of the hiroshima A bomb. Radiat. Res. 145:501-507 (1996). [abstract]

Brenner D.J., Hall E.J., Randers-Pehrson G., Huang Y., Johnson G.W., Miller R.W., Wu B., Vazquez M.E., Medvedovsky C. and Worgul B.V. Quantitative comparisons of continuous and pulsed low dose-rate regimens in a model late-effect system. Int. J. Radiat. Oncol. Biol. Phys. 34:905-910 (1996). [abstract] [PDF 494 KB]

Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Hall E.J., and Sachs R.K. A convenient extension of the linear-quadratic model to include redistribution and reoxygenation. Int. J. Radiat. Oncol. Biol. Phys. 32:379-390 (1995). [abstract] [PDF 1007 KB]

Brenner D.J., Miller R.C., Huang Y. and Hall E.J. The biological effectiveness of radon-progeny aplha particles. III. Quality factors. Radiat. Res. 142:61-69 (1995). [abstract]

Brenner D.J. and Sachs R.K. Chromosomal 'fingerprints' of prior exposure to densely-ionizing radiation. Radiat. Res. 140:134-142 (1994). [abstract]

Brenner D.J., Hall E.J., Huang Y.P., and Sachs R.K. Optimizing the time course of brachytherapy and other accelerated radiotherapeutic protocols. Int. J. Radiat. Oncol. Biol. Phys. 29:893-901 (1994). [abstract]

Brenner D.J. The significance of dose rate in assessing the hazards of domestic radon exposure. Health Physics 67:76-79 (1994). [abstract]

Hahnfeldt P., Hearst J.E., Brenner D.J., Sachs R.K., and Hlatky L.R. Polymer models for interphase chromosomes. Proc. Nat. Acad. Sci. USA 90:7854-7858 (1993). [abstract] [PDF 1035 KB]

 
 

Site developed by CE, page last modified by JL on September 6, 2007 .


ñ
top

Search RARAF:

Home | FAQ | History | Personnel | Publications | Annual Reports | Experiment Scheduling | Directions | Contact
Microbeam
| New Developments | Slow Neutrons | Charged Particles | Fast Neutrons | Schedule (PDF)